Extended Data Fig. 2: Solicited local and systemic reactions by baseline seropositivity to SARS-CoV-2 spike protein.

Top panel: Local solicited reactions. Bottom panel: Systemic solicited reactions. Day 0 is the day of vaccination. P = post-vaccination observation period in the clinic. Fever = Mild: 38.0oC to <38.5oC; moderate: 38.5oC to <39.0oC; severe: ≥39.0oC. Feverish = Self-reported feeling of feverishness.