Extended Data Fig. 3: Alignment of the conserved domains in large protein of SGLV.
From: Identification of a new orthonairovirus associated with human febrile illness in China
a, Amino acid sequence alignments of RNA-directed RNA polymerase motifs in orthonairoviruses. Motifs from pre-A to E are marked with black boxes. b, Alignment of the N-terminal of large protein. Ovarian tumor domain (OTU)-like cysteine proteases motif of CCHFV is underlined with gray line, and the N-terminal toposisomerase motif of CCHFV is marked in black box. c, Alignment of the zinc finger motif. The zinc finger motif of CCHFV is marked with black box. d, Alignment of leucine zipper motif. The leucine zipper motif of CCHFV is marked with black box. CCHFV, Crimean-Congo hemorrhagic fever virus; HUGHV, Hughes virus; ERVEV, Erve virus; TDYV, Tamdy virus; TTV1, Tǎchéng tick virus 1; HTV1, Huángpǐ tick virus 1; WTV, Wēnzhōu tick virus.
