Extended Data Fig. 4: Differentially expressed genes in immune cell states.

Top 10 differentially expressed genes (FDR < 0.05, two-tailed Wilcoxon rank-sum test) for each cell state when compared with other cells within the same cell type. Heatmaps are grouped according to the parent cell type of the different states: (a) T cells, (b) B cells, (c) NK cells, (d) monocytes, and (e) dendritic cells. n = 32,341, 7,970, 9,390, 58,557, 14,299, 3,794 cells for T, B, NK, Mono, DC, and MK, respectively. cDC, conventional dendritic cells; pDC, plasmacytoid dendritic cells; AS DC, AXL-SIGLEC6 dendritic cells.