Extended Data Fig. 8: Expression of pro-inflammatory cytokines is not a feature of circulating cytotoxic lymphocytes in COVID-19. | Nature Medicine

Extended Data Fig. 8: Expression of pro-inflammatory cytokines is not a feature of circulating cytotoxic lymphocytes in COVID-19.

From: A single-cell atlas of the peripheral immune response in patients with severe COVID-19

Extended Data Fig. 8

a, UMAP embedding of CD4+ T, CD8+ T, and NK cells colored by expression of canonical pro-inflammatory cytokines IFNG, TNF, CCL3, and CCL4. n = 22,016 cells are plotted from n = 14 biologically independent samples. Dotted lines correspond to the cell type boundaries identified in Fig. 3b. b, Dot plot depicting average and percent expression of canonical cytotoxic lymphocyte pro-inflammatory cytokines by CD8+ T cells from n = 8 COVID-19 samples and n = 6 healthy controls.

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