Extended Data Fig. 3: Constructing single cell resolution trajectories of the human menstrual cycle using mutual information (MI) based approach.
From: Single-cell transcriptomic atlas of the human endometrium during the menstrual cycle
a, Dimension reduction (tSNE) using whole transcriptome data, that is all genes detected, for unciliated epithelia (epi) and stromal fibroblasts (str), respectively, led to identification of four major phases (insets). b, MI between expressions of each gene and time (red) or permutated time (black). Genes were ranked by their MI with time. c, tSNE using ‘time-associated genes’ for epi and str, respectively led to the identification of the same four major phases as in (a) and trajectories of endometrial transformation. In a, c main panels, cells were colored by the day of menstrual cycle (day). Related to Fig. 3.
