Extended Data Fig. 5: Variant allele fractions of somatic variants detected by cfDNA sequencing. | Nature Medicine

Extended Data Fig. 5: Variant allele fractions of somatic variants detected by cfDNA sequencing.

From: Characteristics of anti-CD19 CAR T cell infusion products associated with efficacy and toxicity in patients with large B cell lymphomas

Extended Data Fig. 5

a, b, Comparison of the average VAF of mutations at day 0 (a) and the number of calibrated mutations (b) between clinical response groups. P values were calculated by a two-sided Student’s t-test. c, Raw variant allele frequencies for each patient are shown for >5FMR (above) and <5FMR (below) groups. Lines are colored by clinical response as in Fig. 4a. The grey dashed line represents the 5-fold reduction threshold for each patient.

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