Extended Data Fig. 6: T-cell clonotypic diversity in patients grouped by clinical and molecular response. | Nature Medicine

Extended Data Fig. 6: T-cell clonotypic diversity in patients grouped by clinical and molecular response.

From: Characteristics of anti-CD19 CAR T cell infusion products associated with efficacy and toxicity in patients with large B cell lymphomas

Extended Data Fig. 6

a, The frequency of the top 10 clonotypes for each patient among all cells (above), CD4 T-cells (middle) and CD8 T-cells (below). Box, median ± interquartile range. Whiskers, minimum and maximum. P-values calculated by a two-sided Wilcoxon rank sum test with Benjamini-Hochberg correction. b, Shannon’s clonality score for patients grouped by clinical or molecular response, shown for all cells (above), CD4 T-cells (middle) and CD8 T-cells (below). CR, n = 9. PR/PD, n = 14. >5FMR, n = 8. <5FMR, n = 9. Box, median ± interquartile range. Whiskers, minimum and maximum. P-values calculated by a two-sided Wilcoxon rank sum test with Benjamini-Hochberg correction.

Back to article page