Extended Data Fig. 2: ROC curves of mNGS test performance.
From: Rapid pathogen detection by metagenomic next-generation sequencing of infected body fluids
ROC curves are plotted from validation set data based on a clinical gold standard or composite standard. Data are presented as median true positive rates± the 95% confidence intervals. The 95% confidence interval was obtained via a bootstrap method with 2000 resampling iterations. a, Illumina dataset, bacterial detection (n = 127 samples). b, Nanopore dataset, bacterial detection (n = 43 samples), c, Illumina dataset, fungal detection (n = 127, 32 fungal organisms). d, Nanopore dataset, fungal detection (n = 43, 11 fungal organisms).
