Extended Data Fig. 3: Epidemic evolution without vaccination for different intermittent strategies.

Time evolution of the epidemic, in the absence of vaccination, when two alternative intermittent strategies are enforced, with an average value of \({\cal{R}}_0\) equal to 1.1. The Open-Close strategy (red) switches every month between \({\cal{R}}_0 = 1.27\) and \({\cal{R}}_0 = 0.9\), starting with \({\cal{R}}_0 = 1.27\). The Close-Open strategy (green) does the same, but starts with \({\cal{R}}_0 = 0.9\). a, Time evolution of the fractions of susceptibles, infected and recovered, and dead. b, Daily new cases. c, Active cases. d, Hospital occupancy. e, ICU occupancy. f, Daily deaths.