Extended Data Fig. 10: Survival outcomes by change in ctDNA fraction. | Nature Medicine

Extended Data Fig. 10: Survival outcomes by change in ctDNA fraction.

From: Circulating tumor DNA-guided treatment with pertuzumab plus trastuzumab for HER2-amplified metastatic colorectal cancer: a phase 2 trial

Extended Data Fig. 10: Survival outcomes by change in ctDNA fraction.

(a) Kaplan-Meier plots of OS for patients with decreased versus increased ctDNA fraction. (b) Forest plots depicting the association between proportional change in ctDNA fraction and PFS. The dot and error bars represent the point estimate of hazard ratio and 95% confidence intervals, respectively. (c) Forest plots depicting the association between proportional change in ctDNA fraction and OS. The dot and error bars represent the point estimate of hazard ratio and 95% confidence intervals, respectively.

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