Fig. 3: nAb titers (pseudovirus ID50; D614G) after the primary series and after a booster injection of 50 µg of mRNA-1273 (per-protocol set).
From: Immune response to SARS-CoV-2 after a booster of mRNA-1273: an open-label phase 2 trial
The nAb titers in the pseudovirus assay against the D614G virus are shown for serum samples collected in part A at baseline, 28 days after the first dose of mRNA-1273, 28 days after the second dose of mRNA-1273 and in part B before the booster injection of 50 µg of mRNA-1273 (pre-booster) and 28 days after the booster injection. Titers from the group that received two priming doses of 50 µg of mRNA-1273 are shown in green, and those from the group that received two priming doses of 100 µg of mRNA-1273 are shown in blue. The dots show the results from individual serum samples. The tops of the bars show the GMTs. The whiskers were determined using the Tukey method. The tops of the whiskers show the 75th percentile minus the IQR (the difference between the 25th and 75th percentiles). The bottoms of the whiskers show the 25th percentile minus the IQR. Antibody values in the pseudovirus assay reported as below the LLOQ (18.5) were replaced by 0.5× LLOQ. Values that were greater than the ULOQ (45,118) were changed to the ULOQ if actual values were not available.
