Table 2 Smoking cessation outcomes
E-cigarettes (n = 571) | NRT (n = 569) | RR (95%CI)a | |
|---|---|---|---|
Primary outcome | |||
Validated prolonged abstinence at EOP, n (%) | 39 (6.8) | 25 (4.4) | 1.55 (0.95–2.53) P = 0.08 |
Sensitivity analyses | |||
Per protocol, n (%) (n = 483 and 382, respectively) | 39 (8.1) | 23 (6.0) | 1.34 (0.82–2.21) P = 0.25 |
Multiple imputation (%) | (9.9) | (7.1) | 1.39 (0.90–2.14) P = 0.13 |
Abstinent participants using non-allocated products excluded, n (%) (n = 571 and 564, respectively) | 39 (6.8) | 20 (3.6) | 1.93 (1.14–3.26) P = 0.02 |
Secondary outcomes | |||
Self-reported abstinence at 4 weeks, n (%) | 89 (15.6) | 61 (10.7) | 1.45 (1.07–1.97) P = 0.02 |
Self-reported prolonged abstinence at EOP, n (%) | 63 (11.0) | 44 (7.7) | 1.43 (0.99–2.06) P = 0.06 |
Validated PP abstinence at EOP, n (%) | 58 (10.2) | 40 (7.0) | 1.44 (0.98–2.13) P = 0.06 |
Self-reported PP abstinence at EOP, n (%) | 118 (20.7) | 78 (13.7) | 1.51 (1.16–1.96) P = 0.002 |
Sensitivity analyses with exclusion of abstinent participants using non-allocated products | |||
Self-reported abstinence at 4 weeks, n (%) (n = 570 and 556, respectively) | 88 (15.4) | 48 (8.6) | 1.79 (1.28–2.49) P = 0.001 |
Self-reported prolonged abstinence at EOP, n (%) (n = 569 and 556, respectively) | 61 (10.7) | 31 (5.6) | 1.92 (1.27–2.92) P = 0.002 |
Validated PP abstinence at EOP, n (%) (n = 569 and 558, respectively) | 56 (9.8) | 29 (5.2) | 1.89 (1.23–2.92) P = 0.004 |
Self-reported PP abstinence at EOP, n (%) (n = 565 and 544, respectively) | 112 (19.8) | 53 (9.7) | 2.03 (1.50–2.76) P < 0.001 |
