Table 3 Treatment adherence

From: Electronic cigarettes versus nicotine patches for smoking cessation in pregnancy: a randomized controlled trial

 

E-cigarettes (n = 571)

NRT (n = 569)

RR (95%CI)a

TQD set, n (%)

418 (73.2)

394 (69.2)

1.06 (0.98–1.14) P = 0.14

Support sessions completed, median (IQR)

1 (0–3)

1 (0–2)

0 (−0.31 to 31)b P = 1.00

Allocated product use, n (%)

Did not use allocated product at all

88 (15.4)

184 (32.3)

0.48 (0.38–0.60) P < 0.001

Request after the initial 2 week supply

315 (55.2)

207 (36.4)

1.52 (1.33–1.73) P < 0.001

Current use at 4 weeks

228 (39.9)

128 (22.5)

1.78 (1.48–2.13) P < 0.001

Regular use during studyc

438 (76.7)

292 (51.3)

1.49 (1.36–1.64) P < 0.001

Current use at end of pregnancy

193 (33.8)

32 (5.6)

6.01 (4.21–8.58) P < 0.001

Non-allocated product use, n (%)

Current use at 4 weeks

11 (1.9)

56 (9.8)

0.20 (0.10–0.37) P < 0.001

Regular use during studyc

16 (2.8)

101 (17.8)

0.16 (0.09–0.26) P < 0.001

Current use at EOP

4 (0.7)

49 (8.6)

0.08 (0.03–0.22) P < 0.001

  1. EOP, end of pregnancy; TQD, target quit date.
  2. Bold, statistically significant results.
  3. aRelative risk obtained using a binomial regression with a logarithmic link with two-sided P values.
  4. bMedian difference (95%CI).
  5. cUsed for 5+ days during the first 4 weeks or at end of pregnancy, using currently or have used regularly for at least 1 week or occasionally for at least 3 weeks.
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