Table 1 Characteristics of individuals tested in outpatient settings with and without SGTF, 15 December 2021 to 17 January 2022 and 3 February to 17 March 2022

From: Clinical outcomes associated with SARS-CoV-2 Omicron (B.1.1.529) variant and BA.1/BA.1.1 or BA.2 subvariant infection in Southern California

Characteristic

Number of individuals (%)

 

15 December 2021 to 17 January 2022

3 February to 17 March 2022

No SGTF (Delta)

SGTF (Omicron)

No SGTF (BA.2)

SGTF (BA.1*)

  

n = 23,305

n = 222,688

n = 1,905

n = 12,756

Age

 

<1 year

391 (1.7)

1,174 (0.5)

53 (2.8)

157 (1.2)

 

1–4 years

1,023 (4.4)

6,579 (3.0)

104 (5.5)

608 (4.8)

 

5–9 years

1,321 (5.7)

12,235 (5.5)

89 (4.7)

904 (7.1)

 

10–19 years

3,218 (13.8)

28,510 (12.8)

217 (11.4)

1,432 (11.2)

 

20–29 years

3,096 (13.3)

37,894 (17.0)

197 (10.3)

1,393 (10.9)

 

30–39 years

3,942 (16.9)

45,165 (20.3)

315 (16.5)

2,421 (19.0)

 

40–49 years

3,770 (16.2)

37,685 (16.9)

271 (14.2)

2,090 (16.4)

 

50–59 years

3,310 (14.2)

29,205 (13.1)

272 (14.3)

1,624 (12.7)

 

60–69 years

1,973 (8.5)

15,767 (7.1)

230 (12.1)

1,240 (9.7)

 

70–79 years

802 (3.4)

5,946 (2.7)

102 (5.4)

632 (5.0)

 

≥80 years

264 (1.1)

1,564 (0.7)

39 (2.0)

218 (1.7)

Sex

 

Female

12,926 (55.5)

123,227 (55.3)

1,040 (54.6)

6,844 (53.7)

 

Male

10,379 (44.5)

99,461 (44.7)

865 (45.4)

5,912 (46.3)

Race/ethnicity

 

White, non-Hispanic

5,788 (24.8)

49,411 (22.2)

504 (26.5)

3,354 (26.3)

 

Black, non-Hispanic

1,552 (6.7)

17,066 (7.7)

109 (5.7)

737 (5.8)

 

Hispanic

11,792 (50.6)

111,574 (50.1)

858 (45.0)

6,041 (47.4)

 

Asian/Pacific Islander

1,954 (8.4)

23,406 (10.5)

256 (13.4)

1,489 (11.7)

 

Other, mixed race or unknown race

2,219 (9.5)

21,231 (9.5)

178 (9.3)

1,135 (8.9)

Community median incomea

 

<$50,000

3,427 (15.0)

34,364 (15.7)

306 (16.5)

1,950 (15.6)

 

$50,000–$99,999

14,271 (62.4)

133,710 (60.9)

1,059 (57.1)

7,459 (59.7)

 

$100,000–$149,999

4,613 (20.2)

45,318 (20.6)

445 (24.0)

2,694 (21.6)

 

≥$150,000

551 (2.4)

6,131 (2.8)

46 (2.5)

390 (3.1)

Cigarette smokinga

 

Never smoker

14,172 (81.3)

134,059 (81.7)

1,120 (79.0)

7,796 (80.8)

 

Current smoker

723 (4.1)

6,865 (4.2)

63 (4.4)

340 (3.5)

 

Former smoker

2,535 (14.5)

23,150 (14.1)

234 (16.5)

1,512 (15.7)

Body mass index (kg m−2)a

 

Underweight (<18.5)

1,808 (10.2)

14,647 (8.8)

156 (10.4)

1,226 (12.0)

 

Normal weight (18.5–24.9)

4,138 (23.3)

41,117 (24.8)

374 (24.9)

2,436 (23.8)

 

Overweight (25.0–29.9)

4,955 (27.9)

46,796 (28.2)

441 (29.4)

2,895 (28.3)

 

Obese (≥30)

6,863 (38.6)

63,212 (38.1)

530 (35.3)

3,669 (35.9)

Prior year outpatient visits

 

0–4

7,973 (34.2)

80,388 (36.1)

480 (25.2)

3,518 (27.6)

 

5–9

6,190 (26.6)

61,656 (27.7)

465 (24.4)

3,343 (26.2)

 

10–14

3,504 (15.0)

31,883 (14.3)

333 (17.5)

1,990 (15.6)

 

15–19

1,948 (8.4)

17,634 (7.9)

183 (9.6)

1,270 (10.0)

 

≥20–29

3,690 (15.8)

31,127 (14.0)

444 (23.3)

2,635 (20.7)

Prior year emergency department visits

 

0

18,402 (79.0)

184,658 (82.9)

1,434 (75.3)

10,264 (80.5)

 

1

3,340 (14.3)

27,489 (12.3)

302 (15.9)

1,704 (13.4)

 

2

957 (4.1)

6,632 (3.0)

98 (5.1)

467 (3.7)

 

≥3

606 (2.6)

3,909 (1.8)

71 (3.7)

321 (2.5)

Prior year inpatient admissions

 

0

22,497 (96.5)

216,532 (97.2)

1,829 (96.0)

12,265 (96.2)

 

1

431 (1.8)

3,330 (1.5)

34 (1.8)

254 (2.0)

 

2

209 (0.9)

1,388 (0.6)

19 (1.0)

115 (0.9)

 

≥3

168 (0.7)

1,438 (0.6)

23 (1.2)

122 (1.0)

Charlson comorbidity index

 

0

18,502 (79.4)

181,317 (81.4)

1,455 (76.4)

9,884 (77.5)

 

1–2

3,836 (16.5)

34,691 (15.6)

336 (17.6)

2,231 (17.5)

 

3–5

710 (3.0)

5,051 (2.3)

74 (3.9)

466 (3.7)

 

≥6

257 (1.1)

1,629 (0.7)

40 (2.1)

175 (1.4)

Prior SARS-CoV-2 infectionb

 

No documented prior infection

23,221 (99.6)

221,525 (99.5)

1,898 (99.6)

12,681 (99.4)

 

Documented prior infection

84 (0.4)

1,163 (0.5)

7 (0.4)

75 (0.6)

COVID-19 vaccination

 

Unvaccinated

9,802 (42.1)

65,480 (29.4)

594 (31.2)

3,858 (30.2)

 

Ad.26.COV2.S—1 dose

717 (3.1)

6,874 (3.1)

34 (1.8)

273 (2.1)

 

Ad.26.COV2.S—with any booster dose

170 (0.7)

2,329 (1.0)

38 (2.0)

203 (1.6)

 

BNT162b2 or mRNA-1273—1 dose

646 (2.8)

6,266 (2.8)

33 (1.7)

287 (2.2)

 

BNT162b2 or mRNA-1273—2 doses (≥180 days prior)

7,492 (32.1)

81,266 (36.5)

424 (22.3)

2,826 (22.2)

 

BNT162b2 or mRNA-1273—2 doses (91–180 days prior)

1,600 (6.9)

18,409 (8.3)

94 (4.9)

863 (6.8)

 

BNT162b2 or mRNA-1273—2 doses (≤90 days prior)

622 (2.7)

8,548 (3.8)

47 (2.5)

625 (4.9)

 

BNT162b2 or mRNA-1273—3 doses

2,256 (9.7)

33,516 (15.1)

641 (33.6)

3,821 (30.0)

  1. SGTF is interpreted as a proxy for SARS-CoV-2 variant.
  2. aMultiple imputation was used to address missing data; numbers may not sum to column totals where missing values occur. The number of missing observations for each variable is specified in Supplementary Table 21.
  3. bPrior infection is defined as any positive test result or diagnosis ≥90 days before the date of the current test.