Extended Data Fig. 4: Time course of cross-sectional area of the target lesion of individual patients.
From: Intratumoral oncolytic herpes virus G47∆ for residual or recurrent glioblastoma: a phase 2 trial
a Cross-sectional area (CSA) of the target lesion expressed as actual area at every assessment point. The median CSA of the tumor at baseline was 519.9 mm2 (range, 122.4-2,306.7 mm2). b CSA of the target lesion expressed as a ratio relative to the pre-treatment area. The target lesions tended to show a temporary increase in area during G47∆ treatment. Twelve patients (63.2%) showed a decrease in target lesion area for a certain time compared to pre-treatment. In patients who did not receive G47∆ for the maximum of 6 times, the period during which they were not administered is expressed as a horizontal dotted line. * indicates patients who received corticosteroids.
