Extended Data Fig. 7: 5-year incidence estimates of COPD, migraine, prostate cancer, and schizophrenia in FinnGen and UK Biobank (UKBB) compared to the population incidence estimates from the Global Burden of Disease Study 2019 for Finland 2019 (GBD). | Nature Medicine

Extended Data Fig. 7: 5-year incidence estimates of COPD, migraine, prostate cancer, and schizophrenia in FinnGen and UK Biobank (UKBB) compared to the population incidence estimates from the Global Burden of Disease Study 2019 for Finland 2019 (GBD).

From: Genetic risk factors have a substantial impact on healthy life years

Extended Data Fig. 7

Number of new cases per 100,000 was calculated as number of new cases per 100,000 during each age interval divided by person-years contributed by individuals that were not cases in the earlier age intervals. The incidence of some diseases like prostate cancer is well captured in UKB and FinnGen, while other disease, such as migraine, as severely under-estimated. Schizophrenia incidence is elevated in FinnGen as one of the legacy cohorts recruited individuals with a psychotic illness.

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