Extended Data Fig. 10: Association of ILT2 and PD-L1 transcripts with pathologic response at baseline and at surgery by tumor histology. | Nature Medicine

Extended Data Fig. 10: Association of ILT2 and PD-L1 transcripts with pathologic response at baseline and at surgery by tumor histology.

From: Neoadjuvant atezolizumab for resectable non-small cell lung cancer: an open-label, single-arm phase II trial

Extended Data Fig. 10: Association of ILT2 and PD-L1 transcripts with pathologic response at baseline and at surgery by tumor histology.The alternative text for this image may have been generated using AI.

Expression values for each transcript are presented as log2 (cpm + 1). Two-sided P-values for Pearson (R) and Spearman (ρ [Rho]) correlation are shown. The grey band represents the 95% confidence interval for the linear regression line. No adjustment was made for multiplicity. Of the 54 patients at baseline with RNA-seq data, 52 also had pathologic response data available. ILT2 is also known as LILRB1 and PD-L1 as CD274. CD, cluster of differentiation; cpm, counts per million reads mapped; ILT2, immunoglobulin-like transcript 2; LILR1, leukocyte immunoglobulin-like receptor 1; MPR, major pathologic response; PD-L1, programmed death-ligand 1; RNA-seq, ribonucleic acid sequencing.

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