Fig. 5: Model validation for the data-rich scenario. | Nature Medicine

Fig. 5: Model validation for the data-rich scenario.

From: The Burden of Proof studies: assessing the evidence of risk

Fig. 5: Model validation for the data-rich scenario.The alternative text for this image may have been generated using AI.

a, Estimated risk curves across 100 realizations for all methods for non-log linear risks. b, Estimated risk curves across 100 realizations for all methods for log linear risks. Mrtool is the method used in this paper. Dosresmeta_1stage_ncs refers to the Dosresmeta package with a natural cubic spline, while Dosresmeta_1stage_qs refers to the same tool with a quadratic spline. Dosresmeta_2stage refers to the the 2 stage approach in Dosresmeta. Metafor refers to a standard package that assumes a log linear relationship. (See ’Model validation’ for more details).

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