Fig. 3: Time-dependent association of AF and abnormal PPG measurements with MACCE.
From: Smartphone-based screening for atrial fibrillation: a pragmatic randomized clinical trial

PPG-detected AF refers to ECG-confirmed AF that was initially detected based on an abnormal PPG measurement. For this analysis, Cox regression analysis was used, and AF, PPG-detected AF and abnormal PPG were introduced as time-dependent covariates in the model. Differences were considered statistically significant when the two-sided P value was less than 0.05. No adjustments were made for multiple comparisons. The analysis was performed for all participants (n = 5,551). During the entire follow-up period, 135 participants developed AF, 62 had PPG-detected AF and 179 had abnormal PPG measurements. Due to censoring, the numbers can slightly differ from those in Extended Data Table 1. Error bars indicate 95% CI.