Extended Data Table 3 CSF MTBR-tau282/t-tau biomarker positivity based on clinical syndromes in pathologically-confirmed cohort

From: CSF tau microtubule-binding region identifies pathological changes in primary tauopathies

  1. Numbers in parenthesis indicate individuals with CSF MTBR-tau282/t-tau decreased compared to cutoff value (0.01220). NC: normal control, FTLD-TDP: frontotemporal lobar degeneration with TAR DNA-binding protein, PiD: Pick’s disease, AGD: argyrophilic grain disease, PSP: progressive supranuclear palsy, CBD: corticobasal degeneration, FTLD-MAPT: frontotemporal lobar degeneration with MAPT mutations (P301L, S305I), bvFTD: behavioral variant of frontotemporal dementia, CBS: corticobasal syndrome, nfvPPA: nonfluent variant primary progressive aphasia, PAGF: pure akinesia with gait freezing, PSP-RS: Progressive supranuclear palsy with Richardson’s Syndrome, CN: cognitively normal.
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