Extended Data Fig. 3: Correlation in genetic architecture between association statistics for anti-Spike and anti-RBD in individuals vaccinated with ChAdOx nCov-19 in COV001 and COV002.

Comparison of –log(10) P-values (a) and beta coefficients (b) for genotyped and imputed variants tested using linear regression within 4 Mb window of top associated variant associated with RBD (rs1130456). Points are coloured by linkage disequilibrium (r²) with rs1130456 and the index variant is shaped as a triangle compared to all other variants as circles.