Fig. 5: Independent dataset validation of lower antibody production in PASC.
From: Molecular states during acute COVID-19 reveal distinct etiologies of long-term sequelae
Plot of linear model coefficients and P values (two-sided t-test, d.f. = 126, no adjustment for multiple testing) for prediction of the product of total IgM and total IgG3 (n = 134 individuals, 85 with PASC). The y axis lists all non-intercept coefficients, including presence of PASC, titers of antibodies against the S1 domain of the spike protein, severity, ICU admission, sex and age. The x axis shows the coefficient values, with the black center point showing the fitted value and the error bars showing the 95% confidence interval (CI) about this value. CIs that include 0 are colored red, whereas those that indicate a significant difference from 0 (P < 0.05) are colored blue.
