Extended Data Fig. 6: QQ-plots, binary analyses (FinnGen).
From: Genetic predictors of lifelong medication-use patterns in cardiometabolic diseases
Two-sided -log10-transformed P values of binary SAIGE mixed-model GWASs for a) Changing simvastatin to another statin b) Discontinuation of statin use c) Discontinuation of hypertension medication use d) Hypertension medications from more than 1 different therapeutic group e) Hypertension medications from more than 2 different therapeutic groups f) Hypertension medications from more than 3 different therapeutic groups g) Hypertension medications from all 4 therapeutic groups h) Using 2nd line type 2 diabetes medications i) Using insulin in type 2 diabetes. The error bands indicate 95% confidence intervals for the quantiles of a normal distribution.
