Extended Data Fig. 5: Volcano plot of tumor region mRNA expression changes of matched untreated control prostatectomies versus post-treatment prostatectomies by Nanostring PanCancer IO 360 analysis.
From: Neoadjuvant enoblituzumab in localized prostate cancer: a single-arm, phase 2 trial
Genes that remained significant after Benjamini and Yekutieli False Discovery Rate (FDR, adjusted p < 0.01) are in blue and labeled. Matched 1:1 untreated controls by grade group, stage, margins, block age [within 2 years], age [within 2 years], and self-reported race. Tumor regions isolated by macrodissection.
