Extended Data Fig. 3: Immune Trait clustering and Module assignment.
From: An integrated tumor, immune and microbiome atlas of colon cancer
Pairwise Pearson correlation matrix of the 103 immune traits. Seven clusters of highly correlated immune traits were defined as Immune Modules: Myeloid signatures (M1), lymphocyte infiltration signatures (M2), IFN response and immune checkpoints (M3), HLA-antigen presentation signatures (M4), TGF-β response and myeloid signatures (M5), wound healing and proliferation-related immune traits (M6) and three separately clustered signatures (M7). Top annotation displays the Immune traits with their respective Immune module (M1-M7), Immune Trait Module and corresponding immune trait categories (as described in Sayaman et al, 2021).
