Extended Data Fig. 2: Manhattan plots of preeclampsia/eclampsia and gestational hypertension in discovery cohorts. | Nature Medicine

Extended Data Fig. 2: Manhattan plots of preeclampsia/eclampsia and gestational hypertension in discovery cohorts.

From: Polygenic prediction of preeclampsia and gestational hypertension

Extended Data Fig. 2: Manhattan plots of preeclampsia/eclampsia and gestational hypertension in discovery cohorts.The alternative text for this image may have been generated using AI.

Manhattan plots (chromosomal position on the X-axis and -log(10) of the P value on the Y-axis) are displayed for (a) preeclampsia/eclampsia in 17,150 cases and 451,241 controls and (b) gestational hypertension in 8,961 cases and 184,925 controls. Analyses included multi-ancestry meta-analysis of common variants (minor allele frequency ≥1%). Loci are labeled by the gene nearest to the lead variant. Two-sided P values (not adjusted for multiple comparisons) are from Z scores from fixed-effect inverse-variance weighted meta-analysis.

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