Fig. 2: Astrocyte reactivity impacts the association of Aβ with tau–PET deposition. | Nature Medicine

Fig. 2: Astrocyte reactivity impacts the association of Aβ with tau–PET deposition.

From: Astrocyte reactivity influences amyloid-β effects on tau pathology in preclinical Alzheimer’s disease

Fig. 2: Astrocyte reactivity impacts the association of Aβ with tau–PET deposition.

a, Voxel-wise regression analysis showing the association between Aβ–PET and tau–PET in individuals classified as negative (Ast−) or positive (Ast+) for astrocyte reactivity (n = 147). b, Percentage of the extent of the brain region with significant association (after RFT correction) between tau–PET and Aβ–PET in each Braak region. Associations were tested using voxel-wise linear regression models corrected for RFT multiple comparison and adjusted by age and sex. RFT, random field theory.

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