Fig. 3: Astrocyte reactivity potentiates longitudinal tau tangle accumulation. | Nature Medicine

Fig. 3: Astrocyte reactivity potentiates longitudinal tau tangle accumulation.

From: Astrocyte reactivity influences amyloid-β effects on tau pathology in preclinical Alzheimer’s disease

Fig. 3: Astrocyte reactivity potentiates longitudinal tau tangle accumulation.

a, Longitudinal tau–PET annual rate of change according to astrocyte reactivity status (n = 71). b, Association between tau–PET annual rate of change and baseline Aβ–PET according to astrocyte reactivity status. c, Percentage of voxels with significant association (after RFT correction) between tau–PET annual rate of change and baseline Aβ–PET in each Braak region. Associations were tested using voxel-wise linear regression models corrected for RFT multiple comparison and adjusted by age and sex.

Back to article page