Extended Data Table 4 Associations between plasma p-tau231 and p-tau217 and Aβ burden according to astrocyte reactivity status

From: Astrocyte reactivity influences amyloid-β effects on tau pathology in preclinical Alzheimer’s disease

  1. Abbreviations: Ast−: reactive astrocyte negative; Ast+: reactive astrocyte positive; p-tau: phosphorylated tau. Covariates: age, sex, and cohort. We inverted the values for plasma Aβ ratio in the analysis to pool plasma Aβ and Aβ-PET levels together. P-values were computed using linear regression models adjusted by age, sex and cohort (when appropriate) for individuals classifies as Ast− and Ast+. In addition, the Aβ burden × astrocyte reactivity status interaction was also computed.
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