Extended Data Fig. 2: Lipids that responded to therapy in serum of patient 1. | Nature Medicine

Extended Data Fig. 2: Lipids that responded to therapy in serum of patient 1.

From: Enasidenib treatment in two individuals with D-2-hydroxyglutaric aciduria carrying a germline IDH2 mutation

Extended Data Fig. 2: Lipids that responded to therapy in serum of patient 1.

Phospholipid species included phosphatidylcholine (PC; a) and phosphatidylethanolamine (PE; b) plasmalogens as well as sphingomyelins (SM; c). Molecules are designated by the sums of acyl and alkyl residues (www.lipidmaps.org/data/classification/lipid_cns.html). For example, PC O-38:5 refers to several molecular species, notably PC O-18:0/20:5, PC O-16:0/22:5 and/or PC O-18:1/20:4.

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