Table 2 Summary of number of diseases associated with alcohol consumption by ICD-10 chapter, in men

From: Alcohol consumption and risks of more than 200 diseases in Chinese men

    

Ever-regular versus occasional drinking

Dose–response associations among current drinkers

Totala

ICD-10 chapter

No. of diseases

Total no. of events

No. of events in current drinkers

Positive

Negative

Positive

Negative

Positive

Negative

I Infectious and parasitic

7

8,010

2,501

1

0

1

0

1

0

II Neoplasms

27

26,064

9,437

9

0

5

0

10

0

III Blood and immune-related

3

1,596

527

0

0

2

0

2

0

IV Endocrine, nutritional and metabolic

6

15,645

5,227

1

1

2

0

2

1

V Psychiatric and behavioral

3

1,683

587

0

0

1

0

1

0

VI Nerve-related

7

7,649

2,574

2

0

1

0

2

0

VII Eye and adnexa

7

10,142

3,240

0

0

1

0

1

0

VIII Ear and mastoid process

3

2,131

667

0

0

0

0

0

0

IX Circulatory

26

101,913

30,784

9

0

10

0

14

0

X Respiratory

23

42,993

13,233

3

0

1

0

3

0

XI Digestive

29

39,118

13,624

6

0

6

1

9

1

XII Skin and subcutaneous tissue

4

2,241

789

0

0

1

0

1

0

XIII Musculoskeletal

15

21,240

6,892

3

0

2

0

3

0

XIV Genitourinary

15

18,422

5,419

0

0

0

1

0

1

XVIII Other symptoms, signs and abnormal findings

16

19,881

7,191

2

0

4

0

4

0

XIX Injury, poisoning and other external causes

12

12,509

4,402

3

0

1

0

4

0

XX External causes

4

2,304

763

3

0

4

0

4

0

Total

207

333,541

107,857

42b

1

42c

2

61d

3

  1. aIncluded disease associations from Cox regression analyses either significant (P < 0.05 for diseases classified as alcohol-related by the WHO, FDR-adjusted P < 0.05 for other diseases; two-sided) from the comparison of ever-regular versus occasional drinking or dose–response association analyses within current drinkers.
  2. bOf the 42 diseases showing significant positive associations with ever-regular versus occasional drinking, 23 diseases were classified as alcohol-related by the WHO.
  3. cOf the 42 diseases showing significant positive dose–response associations among current drinkers, 22 diseases were classified as alcohol-related by the WHO.
  4. dOf the 61 diseases showing significant positive associations with alcohol, 28 diseases were classified as alcohol-related by the WHO (of which 25 diseases passed FDR significance at FDR-adjusted P < 0.05 and 3 diseases were nominally significant at P < 0.05).