Table 1 Baseline demographic and clinical characteristics

From: Machine learning for ECG diagnosis and risk stratification of occlusion myocardial infarction

 

Derivation and testing cohort (n = 4,026)

External validation cohort (n = 3,287)

Age (years)

59 ± 16 (18−102)

60 ± 15 (21−100)

Sex

 Male

2,122 (53%)

1,814 (55%)

 Female

1,904 (47%)

1,473 (45%)

Race

 White

1,698 (42%)

1,326 (40%)

 Black

1,328 (33%)

1,544 (47%)

 Others

52 (1.3%)

40 (1%)

 Unknown

948 (24%)

377 (12%)

Ethnicity

 Not Hispanic

3,043 (76%)

2,850 (87%)

 Hispanic / Latino

19 (1%)

116 (3.5%)

 Unknown

964 (23%)

321 (9.5%)

Past medical history

 Hypertension

2,767 (69%)

2,090 (64%)

 Diabetes

1,146 (29%)

1,067 (33%)

 High cholesterol

1,520 (38%)

1,376 (42%)

 Current smoker

1,244 (31%)

802 (25%)

 Known CAD

1,388 (35%)

964 (30%)

 Prior myocardial infarction

930 (23%)

929 (29%)

 Prior PCI

963 (24%)

134 (4%)

 Prior CABG

357 (10%)

470 (14%)

ECG and laboratory findings

 Sinus rhythm

3,496 (87%)

2,614 (80%)

 Atrial fibrillation

354 (9%)

352 (11%)

 Left BBB

94 (2.3%)

114 (3.5%)

 Right BBB

237 (5.9%)

215 (6.6%)

 ECG-LVH

383 (9.5%)

467 (14.2%)

 cTnI positive (initial)

330 (8.2%)

736 (22.4%)

 cTnI positive (serial testing)

729 (18.1%)

1,177 (35.8%)

Medical therapy

 PCI (any stent)

300 (7.5%)

245 (7.5%)

 Emergent PCI (<90 min)

144 (3.6%)

157 (4.8%)

 Total LAD occlusion

91 (2.3%)

94 (2.9%)

 Total LCX occlusion

63 (1.6%)

88 (2.7%)

 Total RCA occlusion

101 (2.5%)

102 (3.1%)

 CABG

34 (0.8%)

30 (0.9%)

Study outcomes

 Confirmed ACS

550 (13.7%)

537 (16.3%)

OMI

210 (5.2%)

209 (6.4%)

 Other acute myocardial infarction (NOMI)

240 (6.0%)

220 (6.7%)

Unstable angina

100 (2.5%)

108 (3.3%)

 30-d cardiovascular death

137 (3.4%)

111 (3.4%)

  1. Values are mean ± s.d. (minimum–maximum) or n (%). CABG, coronary artery bypass graft; NOMI: non-occlusion myocardial infarction; PCI: percutaneous coronary intervention.