Fig. 3: Immunological profiles.
From: Daratumumab monotherapy for refractory lupus nephritis
a–d, Top panels: Associations of serum. IFN-γ (pg ml−1) (a), sBCMA (ng ml−1) (b), sCD163 (pg ml−1) (c), IL-10 (pg ml−1) (d), and disease activity in SLE patients. Cytochines levels are expressed in ng ml−1. Rs: Spearman’s correlation coefficient, SLEDAI-2K: Systemic Lupus Erythematosus Disease Activity 2000 Index. Middle panel: Correlation matrix heat map of sBCMA and the cytokines IFN-γ, sCD163 and IL-10. Bottom panel: Serum levels of anti-dsDNA (scatter dot plots with results shown as median and range). T0, baseline; T3, 3 months; T6, 6 months; T12, 12 months. The Spearman rank correlation coefficient (rs) was used to assess correlations between parameters. P ≤ 0.05 was considered significant.
