Fig. 3: Spatiotemporal landscape, international linkage and transmission dynamics of the main viral sublineages of MPXV detected in Portugal during the 2022 multi-country mpox outbreak.

a, Characterization of Portuguese genetic subclusters (that is, subclusters including at least two Portuguese sequences) in terms of the number of sequences (and inclusion of sequences from other countries), and their timespan at national and international levels. b, Detail of the temporal landscape of the sequences of main MPXV sublineages (that is, more than ten sequences globally; bold in a). Portuguese cases (in green) reporting travel history are highlighted in black or bright green when the travel-related country matches or does not match a country with sequences in the same cluster, respectively. c, Characterization of the Portuguese genetic subclusters according to the most frequently reported transmission routes and exposure context (excluding cases with no data available), and to potential international linkage based on travel history and/or sexual contact with tourists, travelers or visitors in the 21 days before symptom onset.