Fig. 2: Measures of efficacy in the MDMA-AT and placebo with therapy groups.
From: MDMA-assisted therapy for moderate to severe PTSD: a randomized, placebo-controlled phase 3 trial

a, LS mean change (±s.e.m.) in CAPS-5 total severity score from baseline to after session 3 (primary outcome) for placebo with therapy (n = 50) versus MDMA-AT (n = 53, P < 0.001, Cohen’s d = 0.7). b, LS mean change (±s.e.m.) in SDS total score from baseline to after session 3 (key secondary outcome) for placebo with therapy (n = 50) versus MDMA-AT (n = 53, P = 0.03, Cohen’s d = 0.4).