Extended Data Fig. 6: Urine protein analytes and association with response and survival. | Nature Medicine

Extended Data Fig. 6: Urine protein analytes and association with response and survival.

From: Gemcitabine and cisplatin plus nivolumab as organ-sparing treatment for muscle-invasive bladder cancer: a phase 2 trial

Extended Data Fig. 6: Urine protein analytes and association with response and survival.

(a) Urine Olink protein analyte data. Volcano plot showing the differential expression at time of restaging among patients achieving or not achieving a clinical complete response. The statistical significance or -log10(Pval) is shown on y-axis and log2 protein levels is shown on x-axis. (b) Urine protein analyte data. Volcano plot for overall survival (OS) based levels of protein analytes in the urine at the time of restaging showing log rank test (y-axis) and Cox regression hazard ratio (x-axis). Analytes significant for both tests are shown in pink. A lower hazard ratio (left side of the black line) is associated with reduced risk.

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