Extended Data Fig. 3: Relationship between PD-L1 immunohistochemical staining of pre-treatment transurethral resection of bladder tumor specimens (n = 59) and clinical outcomes.

(a) Relationship between PD-L1 immunohistochemical staining and scoring according to the combined positive score (CPS) and achievement of a clinical complete response (Y, yes; N, no) in 59 patients with available samples for testing. Box and whisker plots demonstrating CPS for patients achieving a clinical complete response (min 0, max 95, median 5, 1^st quartile 1, 3^rd quartile 20) and not achieving a clinical complete response (min 0, max 95, median 1, 1^st quartile 0, 3^rd quartile 5). (b) Kaplan–Meier curve for metastasis-free survival according to PD-L1 expression of baseline TURBT specimens using the cut-point of CPS ≥ 10 versus < 10. (c) Kaplan–Meier curve for overall survival according to PD-L1 expression of baseline TURBT specimens using the cut-point of CPS ≥ 10 versus < 10.