Fig. 2: Parasitological efficacy 4 weeks post treatment. | Nature Medicine

Fig. 2: Parasitological efficacy 4 weeks post treatment.

From: Antimalarial artesunate–mefloquine versus praziquantel in African children with schistosomiasis: an open-label, randomized controlled trial

Fig. 2: Parasitological efficacy 4 weeks post treatment.

Efficacy results are shown as determined by microscopy for praziquantel (PZQ, white diamond) and artesunate–mefloquine (AM, black circle) in participants overall (pooled, n = 718) and infected by S. haematobium (Sh, n = 713) or S. mansoni (Sm, n = 109). a, Estimated cure rates (proportion of participants without any Schistosoma eggs at week 4) with 95% CI. b, Cure rate difference of artesunate–mefloquine compared with praziquantel with 95% CI. The dotted line represents the noninferiority margin for the difference in cure rates. c, Estimated egg reduction rates with 95% bootstrap CI. The striped line represents the efficacy threshold defined by WHO. AM, artesunate–mefloquine; PZQ, praziquantel.

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