Extended Data Fig. 2: Frequency of severe disease in primary versus secondary dengue infections using WHO 1997 and WHO 2009 disease classification.
From: Severe disease during both primary and secondary dengue virus infections in pediatric populations
Data from a subset of the patients from the AIIMS Delhi site where disease severity was classified using both WHO 2009 and WHO 1997 criteria. a, Data shown by WHO 1997 disease classification. Pie charts show the frequency of the cases with dengue shock syndrome (DSS), dengue hemorrhagic fever (DHF); or dengue fever (DF) among a subset of dengue confirmed children that are recruited from AIIMS site among all cases (n = 171), primary dengue cases (n = 66) and secondary dengue cases (n = 105). DSS case frequency is not significantly different between the primary and secondary dengue infections, (p = 0.106, two-sided Fisher’s exact test). b, Data shown by WHO 2009 disease classification among the same group of the patients from panel a. Pie charts show the frequency of the cases with severe dengue (SD), dengue with warning signs (DW); or dengue infection without warning signs (DI) among all cases, primary dengue cases or secondary dengue cases. Severe dengue case frequency was not significantly different between the primary and secondary dengue infections, (p = 0.344, two-sided Fisher’s exact test).
