Extended Data Fig. 2: TOP1 acquired mutations identified in 3 patients at end of treatment.

BOR, best overall response; mo, months; PFS, progression-free survival; PR, partial response; SD, stable disease; TOP1, topoisomerase 1.

BOR, best overall response; mo, months; PFS, progression-free survival; PR, partial response; SD, stable disease; TOP1, topoisomerase 1.