Extended Data Fig. 3: Differential expression of various genes in responders and nonresponders.

chr.loc, chromosome location; HER2, human epidermal growth factor receptor 2; RECIST, Response Evaluation Criteria in Solid Tumors. Results are ordered by statistical value, and genes in Chr 17q12 region are shown as triangles. To identify differentially expressed genes between responder (complete response or partial response) and nonresponder (progressive disease, stable disease, not evaluable) defined by RECIST, moderated t-test was used without multiple testing correction (P ≤ 0.01, absolute log2 FC ≥ 1).