Extended Data Table 6 Summary of arithmetic means (s.d.) of pharmacokinetic parameters after the fifth dose of cadonilimab in combination with chemotherapy

From: Cadonilimab with chemotherapy in HER2-negative gastric or gastroesophageal junction adenocarcinoma: the phase 1b/2 COMPASSION-04 trial

  1. Tmax,ss was reported as the median (minimum, maximum).
  2. AUC0-τ,ss, area under the serum concentration-time curve during a dosing interval; CLss, clearance at steady state; Cmax,ss, the maximum concentration at steady state; Cmin,ss, the minimum concentration at steady state; Rac,AUC and Rac,Cmax, accumulation ratio of AUC0–t,ss to AUC0–t and Cmax,ss to Cmax, respectively; Tmax,ss, time to maximum concentration at steady state; Vss, apparent volume of distribution at steady state.
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