Extended Data Fig. 1: Comparison of catheter ablation systems in the SPHERE Per-AF clinical trial.
From: Dual-energy lattice-tip ablation system for persistent atrial fibrillation: a randomized trial
The investigational Sphere-9TM lattice-tip dual energy catheter with AfferaTM Mapping and Ablation System is shown in the left panel. This system utilizes the Sphere-9TM catheter for both electroanatomical mapping and ablation, employing radiofrequency (red circles) or pulsed field (green circles) energies to create a line of electrical isolation around the pulmonary veins. The control system, depicted in the right panel, consists of a multielectrode mapping catheter for electroanatomical mapping and a separate catheter for radiofrequency ablation (THERMOCOOL® SMARTTOUCH® Surround Flow). As shown in the inserts, the investigational Sphere-9TM catheter has a wider footprint capable for creating wider lesions, resulting in a more contiguous ablation line. LIPV=left inferior pulmonary vein. LSPV=left superior pulmonary vein.
