Extended Data Fig. 3: Waterfall plots showing percent change in body weight from randomization (week 0) to week 24 in each early nonresponder.

Each bar represents the percent change in body weight of an individual participant from randomization (week 0) to week 24. a, The 24-week percent changes in body weight for early nonresponders who were randomized to behavioral treatment (BT) plus placebo. b, The 24-week percent changes in body weight for early nonresponders randomized to BT plus anti-obesity medication (AOM, phentermine = 15.0 mg d⁻¹). c, Both groups combined.