Table 2 Estimated mean percent reduction in body weight, weight loss (kg) and change in BMI from randomization (week 0) and from baseline of the run-in (week −4) in the intention-to-treat population

From: Anti-obesity medication for weight loss in early nonresponders to behavioral treatment: a randomized controlled trial

Variables

BT + P (n = 38)

BT + AOM (n = 38)

Mean difference (95% CI)

Cohen’s d

P value

Change in weight (%)

 From randomization (week 0)

−2.8 ± 0.7

−5.9 ± 0.7

3.1 ± 1.0 (1.1–5.1)

0.72

0.003

 From baseline (week −4)

−3.6 ± 0.8

−6.1 ± 0.8

2.5 ± 1.1 (0.3–4.7)

0.53

0.023

Change in body weight (kg)

 From randomization (week 0)

−2.6 ± 0.7

−5.7 ± 0.7

3.1 ± 1.0 (1.1–5.0)

0.73

0.002

 From baseline (week −4)

−3.8 ± 0.8

−6.2 ± 0.8

2.5 ± 1.1 (0.2–4.7)

0.51

0.032

Change in BMI (kg m−2)

 From randomization (week 0)

−1.0 ± 0.2

−2.1 ± 0.2

1.1 ± 0.3 (0.4–1.8)

0.74

0.002

 From baseline (week −4)

−1.3 ± 0.3

−2.2 ± 0.3

0.9 ± 0.4 (0.1–1.7)

0.52

0.028

  1. Data are estimated as marginal means (±s.e.) for the intention-to-treat population (N = 76) derived from linear mixed models. Suggested interpretation for Cohen’s d—d < 0.2, minimal difference; d of 0.2–0.5, small difference; d of 0.5–0.8, medium difference; d ≥ 0.8, large difference.
Back to article page