Extended Data Fig. 5: Divergence between research and disease burden with a ten-year time lag for research.
From: Global distribution of research efforts, disease burden, and impact of US public funding withdrawal
Time-lagged sensitivity analysis of the declining research-disease divergence (KLD), comparing the distribution of Disability Adjusted Life Years (DALYs) each year with the distribution of research 10 years later (blue line). The first simulation (green line) fixes research while varying the DALY distribution, testing the thought experiment of how the divergence would have evolved, had the research enterprise not changed since 2000. The second simulation (red line) fixes the DALY distribution to 1990 and considers a time-varying research distribution with a 10-year time lag.
