Extended Data Table 2 Participant characteristics by baseline physical activity levels

From: Physical activity as a modifiable risk factor in preclinical Alzheimer’s disease

  1. Baseline participant characteristics were compared across levels of physical activity. For continuous variables, statistical comparisons were performed using one-way ANOVA in unadjusted analyses and using linear regression with Type II ANOVA (F-tests) in analyses adjusted for age and sex. For binary variables, statistical comparisons were performed using Pearson’s Chi-squared tests in unadjusted analyses and using logistic regression with Type II ANOVA (likelihood ratio chi-squared tests) in analyses adjusted for age and sex. Two-tailed p < 0.05 was considered statistically significant without adjustment for multiple comparisons. Aβ = β-amyloid; APOE ε4 = apolipoprotein E ε4 allele; DVR = distribution volume ratio; FLR = frontal, lateral temporal and parietal, and retrosplenial regional uptake; ICV = intracranial volume; PACC5 = Preclinical Alzheimer’s Cognitive Composite-5; PET = positron emission tomography; PiB = Pittsburgh compound-B; PVC = partial volume corrected; SD = standard deviation.
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