Table 1 Demographic and clinical characteristics of patients with cancer across independent cohorts
Demographic and clinical information | UTSW retrospective cohort | UTSW prospective cohort | German validation cohort |
|---|---|---|---|
Patients (n) | 108 | 21 | 1,250 |
Sex, n (%) | |||
Female | 50 (46.3) | 13 (61.9) | 630 (50.4) |
Male | 58 (53.7) | 8 (38.1) | 620 (49.6) |
Race, n (%) | |||
White | 55 (50.9) | 20 (95.2) | 1,237 (99.0) |
Black | 46 (42.6) | 1 (4.8) | – |
Asian | 1 (0.9) | – | 6 (0.5) |
Other | 4 (3.7) | – | 7 (0.6) |
Unknown | 2 (1.9) | – | – |
Ethnicity, n (%) | |||
Non-Hispanic/Latino | 69 (63.9) | 20 (95.2) | 1,250 (100.0) |
Hispanic/Latino | 39 (36.1) | 1 (4.8) | – |
Age, median (Q1, Q3) | 56.0 (49.0,64.2) | 64.0 (58.0,69.0) | 68.0 (60.0,75.5) |
Primary tumor site, n (%) | |||
Lung | 20 (18.5) | 3 (14.3) | 250 (20.0) |
Colorectal | 17 (15.7) | 4 (19.0) | 250 (20.0) |
Pancreas + pancreatobiliary | 3 (2.8) | 4 + 1 (23.8) | 250 (20.0) |
Liver | 11 (10.2) | – | 250 (20.0) |
Ovarian | 1 (0.9) | – | 250 (20.0) |
Breast | 7 (6.5) | 5 (23.8) | – |
Endometrial | 3 (2.8) | 1 (4.8) | – |
Esophagus | 3 (2.8) | 1 (4.8) | – |
Kidney | 3 (2.8) | 1 (4.8) | – |
Prostate | 3 (2.8) | 1 (4.8) | – |
Cholangiocarcinoma | 7 (6.5) | – | – |
Pancreatobiliary of unknown primary | 6 (5.6) | – | – |
Sarcoma | 6 (5.6) | – | – |
Stomach | 5 (4.6) | – | – |
Urinary bladder | 4 (3.7) | – | – |
Cervical | 2 (1.9) | – | – |
Gynecological of unknown primary | 2 (1.9) | – | – |
Thymus | 2 (1.9) | – | – |
Head and neck | 1 (0.9) | – | – |
Thyroid | 1 (0.1) | – | – |
Small bowel | 1 (0.1) | – | – |
Stage at diagnosis, n (%) | |||
I | 2 (1.9) | – | 237 (19.0) |
II | 9 (8.3) | – | 275 (22.0) |
III | 11 (10.2) | 2 (9.5) | 394 (31.5) |
IV | 57 (52.8) | 13 (61.9) | 344 (27.5) |
Unknown | 29 (26.9) | 6 (28.6) | – |
Metastasis, n (%) | |||
No | 11 (10.2) | – | 829 (66.3) |
Yes | 97 (89.8) | 21 (100.0) | 421 (33.7) |
