Extended Data Fig. 1: Longitudinal serum concentration of in vivo-expressed DMAb AZD5396. | Nature Medicine

Extended Data Fig. 1: Longitudinal serum concentration of in vivo-expressed DMAb AZD5396.

From: Safety and pharmacokinetics of SARS-CoV-2 DNA-encoded monoclonal antibodies in healthy adults: a phase 1 trial

Extended Data Fig. 1

Serum DMAb concentrations (ng/mL) measured using a qualified quantitative binding assay are shown for study participants receiving a, a single dose of 0.5 mg or 1 mg on D0; b, two doses of 0.25 mg, 0.5 mg, 1 mg, or 2 mg on D0, 3; or c, four doses of 0.5 mg of SARS-CoV-2 DMAb on D0, 3, 28, 31. Arrows indicate dosing events. d, Mean serum concentrations (±SEM) for each dose group.

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