Extended Data Table 8 Changes in transcriptional activity of pathophysiological pathways in whole blood in CC-genotype participants by treatment arm during the first 60 days from randomization

From: Genotype-stratified adjunctive dexamethasone for tuberculous meningitis in HIV-negative adults: a randomized controlled phase 3 trial

  1. 95% CI: Bayesian 95% credible intervals.
  2. †p-value: Derived from crude “Wald-type” tests, calculated as the posterior mean estimate divided by its standard deviation from the MCMC sampling of coefficients in the joint model. All tests were two-sided.
  3. ††p-values adjusted for multiple comparisons using the Hochberg procedure. CI=confidence interval. IFN=interferon. TNF=tumour necrosis factor.
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